Safety

Despite the wide scale use of ACTs, little is known about their long-term effects. It is important to consolidate the safety profiles of these drugs to document both known and previously unobserved side effects.

Useful resources | Peer-reviewed publications | Projects | News

Useful resources

Training manuals of drug shop trial in Uganda

Use of rapid diagnostic tests by drug shop vendors to improve malaria treatment

Safety data collection tools for real-world reporting

Resources for the collection of safety data by non-clinician and clinician data collectors

PRIME trainer and learner manuals

Nine new workshops, focused on Health Centre Management and Patient Centred Services.

Policy brief and posters for community management project in Uganda

Use of rapid diagnostic tests to improve malaria treatment in the community in Uganda

Outils de collecte de données concrètes sur la sécurité des médicaments

Ressources permettant aux collecteurs de donnes cliniciens et non cliniciens de recueillir des informations sur la scurit des mdicaments

Manuels de formation de l'étude en pharmacie en Ouganda

Utilisation des tests de dpistage rapide par les pharmaciens afin d'amliorer le traitement du paludisme

Manuais de formação para ensaio realizado em postos de venda de medicamentos no Uganda

Utilizao de testes de diagnstico rpido por vendedores de postos de venda de medicamentos para melhorar o tratamento da malria

Peer-reviewed publications

Would rational use of antibiotics be compromised in the era of test-based management of malaria?

Tropical Medicine and International Health

Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence

Malaria Journal

Understanding interpretations of and responses to childhood fever in the Chikhwawa district of Malawi

PLOS ONE

The need for new antibiotics

The Lancet

The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patients

BMC Infectious Diseases

Shifting from presumptive to test-based management of malaria - Technical basis and implications for malaria control in Ghana

Ghana Medical Journal

Seasonal and geographic differences in treatment-seeking and household cost of febrile illness among children in Malawi

The Malaria Journal

Performance of Interferon-Gamma and IP-10 Release Assays for Diagnosing Latent Tuberculosis Infections in Patients with Concurrent Malaria in Tanzania

The American Journal of Tropical Medicine and Hygiene

Perceptions and utilization of the anti-malarials artemether-lumefantrine and dihydroartemisininpiperaquine in young children in the Chikhwawa District of Malawi: A mixed methods study

Malaria Journal

Neuroauditory toxicity of artemisinin combination therapies—Have safety concerns been addressed?

American Journal of Tropical Medicine and Hygiene

Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection

Journal of Pharmaceutical and Biomedical Analysis

Management of febrile children under five years in hospitals and health centres of rural Ghana

Malaria Journal

Interaction between artemether-lumefantrine and nevirapine-based antiretroviral therapy in HIV-1-infected patients

Antimicrobial Agents and Chemotherapy

Integration of data from multiple sources for simultaneous modelling analysis: experience from nevirapine population pharmacokinetics

British Journal of Clinical Pharmocology

Improving access to health care for malaria in Africa: a review of literature on what attracts patients

Malaria Journal

How experiences become data: the process of eliciting adverse event, medical history and concomitant medication reports in antimalarial and antiretroviral interaction trials

BMC Medical Research Methodology

High throughput quantitation of artesunate and its degradation products by flow injection gradient ratio standard addition mass spectrometry (FI-GRSA-MS)†

Analytical Methods

Health facility utilisation changes during the introduction of community case management of malaria in South Western Uganda: An interrupted time series approach

PLOS ONE

Exploring meaning of participation in a clinical trial in a developing country setting: implications for recruitment

Trails Journal

Exploring health providers’ and community perceptions and experiences with malaria tests in South-East Nigeria: a critical step towards appropriate treatment

Malaria Journal

Eliciting harms data from trial participants: how perceptions of illness and treatment mediate recognition of relevant information to report

Trials Journal

Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic Falciparum Malaria infections in Uganda

Journal of Infectious Diseases

Designing adverse event forms for real-world reporting: Participatory research in Uganda

PLoS ONE

Cost-effectiveness analysis of introducing RDTs for Malaria diagnosis as compared to microscopy and presumptive diagnosis in central and peripheral public health facilities in Ghana

The American Journal of Tropical Medicine and Hygiene

Combining data from multiple spatially referenced prevalence surveys using generalized linear geostatistical models

Royal Statistical Society

Challenging logics of complex intervention trials: Community perspectives of a health care improvement intervention in rural Uganda

Social Science & Medicine

Aspirations for quality health care in Uganda: How do we get there?

Human Resources for Health

An evaluation of the clinical assessments of under-five febrile children presenting to primary health facilities in rural Ghana

PLoS ONE

An economic evaluation of home management of Malaria in Uganda: An interactive markov model

PLoS ONE

Accuracy of rapid tests for Malaria and treatment outcomes for Malaria and non-Malaria cases among under-five children in rural Ghana

PLoS ONE

Acceptability of Rapid Diagnostic Test-based management of Malaria among caregivers of under-five children in rural Ghana

PLoS ONE

'… in the project they really care for us': meaning and experiences of participating in a clinical study of first-line treatment for malaria and HIV in Tanzanian adults.

Global Public Health

“Every drug goes to treat its own disease…” - A qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania

Malaria Journal